what is the clothes made of？
Be made of 是有什么制成的【看的出原材料】
例：The desk is made of wood
桌子是由木头制成的
Be made from 是由什么制成【看不出原材料】
例：The book is made of wood
书是由木头制成的
你的那个翻译不符合英语习惯，正确的应该是：
What is this clothes made of?
what is this cloth made of?
what material is this cloth?
What 's this clothing made of?
不是
What's the cloth be made of?
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