可以的,例如,1 He is someone that / who has given us lots of help in the past few years, and we are grateful to him
2 Here is something that you need to know before you operate this machine. Please read it .
He is the only friend in my life with who I have something in commom.
可以的,没有规定说不定代词不可用于定语从句啊。
不,不定代词在定语从句中可以做先行词或修饰先行词。此时从句中关系词用that 不用which